Localised Gingival Overgrowth in Patient taking Amlodipine
PDF

Keywords

Amlodipine
gingival enlargement
gingivectomy

Abstract

Gingival enlargement is an increase in the size of gingiva. It is one of the side effects of systemic administration of antihypertensives, anticonvulsants, and immunosuppressants. Amlodipine, a new third-generation dihydropyridine, very useful in middle-aged to older aged patients for various cardiovascular conditions can cause gingival enlargement. Treatment modalities for drug induced gingival enlargement include removal of local irritating factors, meticulous plaque removal and drug substitution after consultation with a physician. This article reports an amlodipine induced gingival enlargement and its treatment in a 40 years old hypertensive male patient.

PDF

References

Newman MG, Takei H, Klokkevold PR, Carranza FA, editors. Newman and Carranza's Clinical Periodontology. 13th ed. Philadelphia (PA): Saunders, Elsevier; 2018.

Agrawal AA. Gingival enlargements: Differential diagnosis and review of literature. World J Clin Cases. 2015 Sep 16;3(9):779-88.

Kimball OP. The treatment of epilepsy with sodium diphenyl hydantoinate. J Am Med Assoc. 1939;112(13):1244-5.

Harold CE, editor. Physician’s drug handbook. 12th ed. Spring House (PA): Lippincott Williams and Wilkins; 2007.

Levine CB, Fahrbach KR, Frame D, Connelly JE, Estok RP, Stone LR, et al. Effect of amlodipine on systolic blood pressure. Clin Ther. 2003;25(1):35-57.

Tejnani A, Gandevivala A, Bhanushali D, Gourkhede S. Combined treatment for a combined enlargement. J Indian Soc Periodontol. 2014;18(4):516-9.

Ellis JS, Seymour RA, Steele JG, Robertson P, Butler TJ, Thomason JM. Prevalence of gingival overgrowth induced by calcium channel blockers: a community-based study. J Periodontol. 1999 Jan;70(1):63-7.

Jorgensen MG. Prevalence of amlodipine-related gingival hyperplasia. J Periodontol. 1997;68(7):676-8.

Seymour RA, Ellis JS, Thomason JM, Monkman S, Idle JR. Amlodipine induced gingival overgrowth. J Clin Periodontal. 1994;21(4):281-3.

Ellis JS, Seymour RA, Monkman SC, Idle JR. Gingival sequestration of nifedipine in nifedipine-induced gingival overgrowth. Lancet. 1992;339(8806):1382-3.